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| Nomenclature |
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Symbol:
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Tg(Tpbpa-cre,-EGFP)5Jcc
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Name:
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transgene insertion 5, James C Cross
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MGI ID: |
MGI:5287872 |
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Synonyms: |
Tpbpa-Cre, Tpbpa-Cre-GFP |
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Transgene:
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Tg(Tpbpa-cre,-EGFP)5Jcc
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: Transgenic mice were generated using a construct in which a cre recombinase-IRES-EGFP cassette was cloned downstream of the Tpbpa promoter. Three independent lines were obtained and all lines produced similar temporal and spatial expression patterns of cre-EGFP that correlated with those of the endogenous Tpbpa gene. Line 5 was used for further studies as it showed earliest onset of expression (around E8.0). Activity of cre recombinase in reporter assays also was detected by E8.0. (J:122534)
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Recombinase activity
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Activity:
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 Tissue activity of this recombinase allele
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Driver:
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Tpbpa
Summary of all recombinase alleles
driven by Tpbpa.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:122534
Simmons DG et al.,
"Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta."
Dev Biol 2007 Apr 15;304(2):567-78
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All: |
3 reference(s)
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Analysis Tools
