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| Nomenclature |
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Symbol:
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Tg(SOD1*G127X)716Mrkl
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Name:
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transgene insertion 716, Stefan L Marklund
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MGI ID: |
MGI:5286585 |
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Synonyms: |
G127X |
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Transgene:
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Tg(SOD1*G127X)716Mrkl
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6 x CBA
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: An 11.6 kb human SOD1 genomic fragment containing a mutation in exon 5 (Gly127insTGGG) that results in production of a truncated enzyme subunit with five novel amino acids following Gly127 was randomly inserted. This line carries 19 copies of the transgene. (J:175594)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:175594
Jonsson PA et al.,
"Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis."
Brain 2004 Jan;127(Pt 1):73-88
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All: |
2 reference(s)
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Analysis Tools
