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| Nomenclature |
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Symbol:
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Mettm1Ics
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Name:
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met proto-oncogene;
targeted mutation 1, Mouse Clinical Institute
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MGI ID: |
MGI:5285647 |
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Synonyms: |
MetLacZ |
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Gene:
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Met
Location:
Chr6:17463800-17573980 bp, + strand
Genetic Position: Chr6,
7.83 cM, cytoband A2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:174591
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutations: | |
Insertion, Duplication |
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Mutation details: A cassette containing a loxP site, duplicated exon 12, and a neo cassette with 3 polyadenylation sequences and a 3' loxP site was inserted upstream of exon 12. An IRES, nuclear localization sequence, and lacZ gene with a polyadenlylation sequence were inserted downstream of exon 12. (J:174591)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Met Mutation:
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4 strains or lines available |
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Notes |
ES cell line = P1 from Institut Clinique de la Souris.
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| References |
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Original: |
J:174591
Lamballe F et al.,
"Pool-specific regulation of motor neuron survival by neurotrophic support."
J Neurosci 2011 Aug 3;31(31):11144-58
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All: |
1 reference(s)
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Analysis Tools
