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| Nomenclature |
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Symbol:
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Amer1tm1.1Nbar
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Name:
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APC membrane recruitment 1;
targeted mutation 1.1, Nabeel Bardeesy
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MGI ID: |
MGI:5086003 |
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Synonyms: |
Wtxlox |
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Gene:
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Amer1
Location:
ChrX:95420318-95444872 bp, - strand
Genetic Position: ChrX,
41.99 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:173242
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Parent Cell Line:
| v6.5 (ES Cell) |
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Strain of Origin:
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(C57BL/6 x 129S4/SvJae)F1
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and second loxP site were inserted in the untranslated region of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:173242)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Amer1 Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:173242
Moisan A et al.,
"The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification."
Dev Cell 2011 May 17;20(5):583-96
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All: |
1 reference(s)
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