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| Nomenclature |
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Symbol:
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Lrrtm1tm1.1Jaru
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Name:
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leucine rich repeat transmembrane neuronal 1;
targeted mutation 1.1, Jun Aruga
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MGI ID: |
MGI:5085889 |
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Gene:
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Lrrtm1
Location:
Chr6:77242689-77257791 bp, + strand
Genetic Position: Chr6,
33.89 cM
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Approach toward inanimate objects is altered in Lrrtm1tm1.1Jaru/Lrrtm1tm1.1Jaru mice
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:174350
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Parent Cell Line:
| CMTI-2 (ES Cell) |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A loxP site was inserted into exon 2 upstream of the translation initiation site. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed the coding region and neo cassette. (J:174350)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Lrrtm1 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:174350
Takashima N et al.,
"Impaired cognitive function and altered hippocampal synapse morphology in mice lacking lrrtm1, a gene associated with schizophrenia."
PLoS One 2011;6(7):e22716
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All: |
1 reference(s)
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Analysis Tools
