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| Nomenclature |
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Symbol:
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Tg(HTT*/EGFP)190Nn
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Name:
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transgene insertion 190, Nobuyuki Nukina
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MGI ID: |
MGI:5052377 |
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Synonyms: |
HD190QG |
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Transgene:
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Tg(HTT*/EGFP)190Nn
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6 x DBA/2
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Transgene
description |
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Transgene
Type: | |
Transgenic (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: The human HTT promoter and exon 1, containing expanded CAG repeats, were fused to EGFP. The expanded repeat segment includes about 150 CAG repeats. This line carries 2 main fragments, one with 190 CAG repeats and one with 155 CAG repeats. (J:174269)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:174269
Kotliarova S et al.,
"Decreased expression of hypothalamic neuropeptides in Huntington disease transgenic mice with expanded polyglutamine-EGFP fluorescent aggregates."
J Neurochem 2005 May;93(3):641-53
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All: |
1 reference(s)
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Analysis Tools
