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| Nomenclature |
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Symbol:
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Tg(Eno2-PSEN2*)1480Ykk
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Name:
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transgene insertion 1480, Yong K Kim
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MGI ID: |
MGI:5052118 |
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Synonyms: |
NSE-hPS2m |
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Transgene:
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Tg(Eno2-PSEN2*)1480Ykk
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A 1.8kb fragment of the rat Eno2 promoter drives expression of a human PSEN2 cDNA with an N141I mutation found in Volga German families. The highest levels of transgene mRNA expression were detected in the anterior brain, followed by posterior brain, muscle, lung, heart, and liver. (J:76934)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:76934
Hwang DY et al.,
"Alterations in behavior, amyloid beta-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease."
FASEB J 2002 Jun;16(8):805-13
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All: |
2 reference(s)
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Analysis Tools
