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| Nomenclature |
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Symbol:
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Tg(Eno2-PSEN2)2348Ykk
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Name:
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transgene insertion 2348, Yong K Kim
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MGI ID: |
MGI:5052116 |
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Synonyms: |
NSE-hPS2w |
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Transgene:
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Tg(Eno2-PSEN2)2348Ykk
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A 1.8kb fragment of the rat Eno2 promoter drives expression of a human PSEN2 cDNA. High levels of mRNA expression were detected in the brain. Expression in the liver, kidney and intestines were higher than in the brain. (J:76934)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:76934
Hwang DY et al.,
"Alterations in behavior, amyloid beta-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease."
FASEB J 2002 Jun;16(8):805-13
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All: |
1 reference(s)
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Analysis Tools
