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| Nomenclature |
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Symbol:
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Rnase10tm1(cre)Hht
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Name:
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ribonuclease, RNase A family, 10 (non-active);
targeted mutation 1, Ilpo Huhtaniemi
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MGI ID: |
MGI:5051834 |
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Gene:
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Rnase10
Location:
Chr14:51007751-51010758 bp, + strand
Genetic Position: Chr14,
26.34 cM, cytoband C1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:173897
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Parent Cell Line:
| AB2.2 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: An iCre and FRT flanked PGK-neomyucin resistance cassette was inserted in exon 2 replacing the first 8 nucleotides which includes the initiation site. Cre expression was confirmed by RT-PCR analysis of RNA samples from segments I and II of the proximal epididymis. (J:173897)
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Recombinase activity
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Driver:
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Rnase10
Summary of all recombinase alleles
driven by Rnase10.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Rnase10 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:173897
Krutskikh A et al.,
"Targeted inactivation of the androgen receptor gene in murine proximal epididymis causes epithelial hypotrophy and obstructive azoospermia."
Endocrinology 2011 Feb;152(2):689-96
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All: |
1 reference(s)
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Analysis Tools
