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| Nomenclature |
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Symbol:
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Msx1tm2.1(cre/ERT2)Bero
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Name:
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homeobox, msh-like 1;
targeted mutation 2.1, Benoit Robert
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MGI ID: |
MGI:5049923 |
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Synonyms: |
Msx1CreERT2, Msx1tm2(cre/ERT2)Bero |
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Gene:
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Msx1
Location:
Chr5:37820485-37824583 bp, - strand
Genetic Position: Chr5,
20.21 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:173525
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Parent Cell Line:
| CK35 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A targeting vector with the cre/ERT2 sequence, polyadenylation site, and an Frt-flanked neomycin cassette inserted into the ATG site of Msx1 in a plasmid was generated by homologous recombination in bacteria. The linearized targeting vector was electroporated into ES cells and targeted clones were used to generated chimeras. F1 offspring were crossed to Flp deleter mice to delete the neo marker. (J:173525, J:194129)
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Recombinase activity
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Driver:
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Msx1
Summary of all recombinase alleles
driven by Msx1.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Msx1 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:173525
Lopes M et al.,
"Msx genes define a population of mural cell precursors required for head blood vessel maturation."
Development 2011 Jul;138(14):3055-66
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All: |
4 reference(s)
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Analysis Tools
