|
|
| Nomenclature |
|
Symbol:
|
Tg(Upk2-TAg)#Rkl
|
|
Name:
|
transgene insertion, Raghu Kalluri
|
|
MGI ID: |
MGI:5014305 |
|
Synonyms: |
UPK II-SV40 |
|
Transgene:
|
Tg(Upk2-TAg)#Rkl
Location:
unknown
|
|
Urothelial carcinoma in situ in Tg(Upk2-TAg)#Rkl/0 mice
Show the 2 image(s) involving this allele.
|
 |
|
Transgene origin |
|
Strain of Origin:
|
C57BL/6
|
|
Transgene description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The mouse promoter drives urinary bladder-specific expression of the SV40 large T antigen with a polyadenylation sequence. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:173505)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:173505
Ayala de la Pena F et al.,
"Loss of p53 and Acquisition of Angiogenic MicroRNA Profile Are Insufficient to Facilitate Progression of Bladder Urothelial Carcinoma in Situ to Invasive Carcinoma."
J Biol Chem 2011 Jun 10;286(23):20778-87
|
|
All: |
1 reference(s)
|
|