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| Nomenclature |
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Symbol:
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Tg(MMTV-ERBB2*,-luc)6157Aami
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Name:
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transgene insertion 6157, Augusto Amici
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MGI ID: |
MGI:5013830 |
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Synonyms: |
delta16HER2-LUC |
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Transgene:
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Tg(MMTV-ERBB2*,-luc)6157Aami
Location:
unknown
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Tg(MMTV-ERBB2*,-luc)6157Aami/0 mice develop spontaneous mammary tumors
Show the 2 image(s) involving this allele.
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The MMTV promoter drives mammary gland-specific expression of human ERBB2 with an in-frame deletion of exon 16 (variant identified in human breast carcinomas) and an IRES-luciferase. Lines 6157, 6177, and 6180 were generated. (J:172352)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:172352
Marchini C et al.,
"The Human Splice Variant Delta16HER2 Induces Rapid Tumor Onset in a Reporter Transgenic Mouse."
PLoS One 2011;6(4):e18727
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All: |
1 reference(s)
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Analysis Tools
