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| Nomenclature |
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Symbol:
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Birc3tm1.1Rbr
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Name:
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baculoviral IAP repeat-containing 3;
targeted mutation 1.1, Robert Brink
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MGI ID: |
MGI:5013655 |
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Gene:
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Birc3
Location:
Chr9:7848699-7873186 bp, - strand
Genetic Position: Chr9,
2.46 cM, cytoband A2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:172843
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Parent Cell Line:
| Bruce 4 (ES Cell) |
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Strain of Origin:
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B6.Cg-Thy1a
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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FLP-mediated recombination removed exon 2, exon 3, and the neo cassette. (J:172843)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Birc3 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:172843
Gardam S et al.,
"Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response."
Blood 2011 Apr 14;117(15):4041-51
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All: |
3 reference(s)
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Analysis Tools
