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| Nomenclature |
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Symbol:
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Rfwd2tm2.1Vmd
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Name:
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ring finger and WD repeat domain 2;
targeted mutation 2.1, Vishva M Dixit
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MGI ID: |
MGI:5013594 |
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Synonyms: |
Cop1fl |
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Gene:
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Rfwd2
Location:
Chr1:159232326-159347580 bp, + strand
Genetic Position: Chr1,
69.03 cM, cytoband C3
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Show the 4 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:172653
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Parent Cell Line:
| C2 (Nagy) (ES Cell) |
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Strain of Origin:
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C57BL/6N
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 3. A floxed neo cassette was inserted downstream of exon 3. Cre-mediated recombination removed the neo cassette. (J:172653)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Rfwd2 Mutation:
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9 strains or lines available |
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| References |
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Original: |
J:172653
Vitari AC et al.,
"COP1 is a tumour suppressor that causes degradation of ETS transcription factors."
Nature 2011 Jun 16;474(7351):403-6
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All: |
1 reference(s)
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Analysis Tools
