|
|
| Nomenclature |
|
Symbol:
|
Id3tm2.1Zhu
|
|
Name:
|
inhibitor of DNA binding 3;
targeted mutation 2.1, Yuan Zhuang
|
|
MGI ID: |
MGI:5009711 |
|
Synonyms: |
Id3f, Id3L |
|
Gene:
|
Id3
Location:
Chr4:136143497-136145755 bp, + strand
Genetic Position: Chr4,
68.34 cM
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:172701
|
|
Parent Cell Line:
| W4 (ES Cell) |
|
Strain of Origin:
|
129S6/SvEvTac
|
|
Mutation description |
|
Allele
Type: | |
Targeted (Floxed/Frt) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exons 1 and 2 floxed. (J:172701)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Id3 Mutation:
|
4 strains or lines available |
|
| References |
|
Original: |
J:172701
Guo Z et al.,
"Modeling Sjogren's syndrome with Id3 conditional knockout mice."
Immunol Lett 2011 Mar 30;135(1-2):34-42
|
|
All: |
4 reference(s)
|
|