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| Nomenclature |
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Symbol:
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Cul9tm1.2Yxi
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Name:
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cullin 9;
targeted mutation 1.2, Yue Xiong
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MGI ID: |
MGI:5007737 |
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Gene:
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Cul9
Location:
Chr17:46500605-46546388 bp, - strand
Genetic Position: Chr17,
22.9 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:170976
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: Cre-medited recombination removed exons 2 through 7 from Cul9tm1.1Yxi. The absence of protein expression was confirmed by western blot analysis. (J:170976)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cul9 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:170976
Pei XH et al.,
"Cytoplasmic CUL9/PARC Ubiquitin Ligase Is a Tumor Suppressor and Promotes p53-Dependent Apoptosis."
Cancer Res 2011 Apr 15;71(8):2969-77
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All: |
1 reference(s)
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