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Apoetm4Mae
Targeted Allele Detail

Nomenclature
Symbol: Apoetm4Mae
Name: apolipoprotein E; targeted mutation 4, Nobuyo Maeda
MGI ID: MGI:5007656
Gene: Apoe   Location: Chr7:19696109-19699166 bp, - strand    Genetic Position: Chr7, 9.94 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:172417
Parent Cell Line: TC1/TC-1 (ES Cell)
Strain of Origin: 129S6/SvEvTac
Mutation
description
Allele Type:   Targeted (knock-out)
Mutations:   Insertion, Intragenic deletion
    Part of exon 3 and intron 3 were replaced with a neomycin resistance cassette. (J:172417)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apoe Mutation: 55 strains or lines available
References
Original: J:172417 Maeda N et al., "Anatomical differences and atherosclerosis in apolipoprotein E-deficient mice with 129/SvEv and C57BL/6 genetic backgrounds." Atherosclerosis 2007 Nov;195(1):75-82
All: 3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory