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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 1, Sean E Egan
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MGI ID: |
MGI:5000472 |
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Synonyms: |
R26-Pik3caH1047R |
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Gene:
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Gt(ROSA)26Sor
Location:
Chr6:113067428-113077333 bp, - strand
Genetic Position: Chr6,
52.73 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:170898
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Parent Cell Line:
| W4 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A construct consisting of a splice acceptor site, a floxed transcriptional stop cassette and a mutant mouse Pik3ca cDNA, encoding for a histidine 1047 arginine substitution, was inserted into intron 1 via homologous recombination. (J:170898)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:170898
Adams JR et al.,
"Cooperation between Pik3ca and p53 Mutations in Mouse Mammary Tumor Formation."
Cancer Res 2011 Apr 1;71(7):2706-2717
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All: |
1 reference(s)
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Analysis Tools
