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| Nomenclature |
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Symbol:
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Tg(AR*100Q)C32Als
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Name:
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transgene insertion C32, Albert La Spada
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MGI ID: |
MGI:5000266 |
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Synonyms: |
AR100, AR YAC CAG100 |
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Transgene:
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Tg(AR*100Q)C32Als
Location:
unknown
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Transgene
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:89772
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The transgene contains a human YAC in which the CAG repeat contains 100 repeats (100Q). Lines C25 (high expressor) and C32 (low expressor) were generated. (J:89772)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:89772
Sopher BL et al.,
"Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration."
Neuron 2004 Mar 4;41(5):687-99
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All: |
2 reference(s)
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Analysis Tools
