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| Nomenclature |
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Symbol:
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Col1a1tm5(tetO-GFP/RNAi:Cdkn2a)Slowe
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Name:
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collagen, type I, alpha 1;
targeted mutation 5, Scott Lowe
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MGI ID: |
MGI:4950584 |
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Synonyms: |
TG-p19.157 |
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Gene:
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Col1a1
Location:
Chr11:94936224-94953042 bp, + strand
Genetic Position: Chr11,
59.01 cM, cytoband D
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:171191
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Parent Cell Line:
| v6.5 (ES Cell) |
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Strain of Origin:
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(C57BL/6 x 129S4/SvJae)F1
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: RMCE on KH2 cells inserted a cassette that contains the tetracycline promoter and a GFP fusion with an Mir30e-based short hairpin sequence targeting Cdkn2a (TG-p19.157) into the 3'UTR. (J:171191)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Col1a1 Mutation:
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64 strains or lines available |
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Notes |
The allele was made in KH2 cells that carry Gt(ROSA)26Sortm1(rtTA*M2)Jae and Col1a1tm2(tetO-Pou5f1)Jae.
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| References |
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Original: |
J:171191
Premsrirut PK et al.,
"A rapid and scalable system for studying gene function in mice using conditional RNA interference."
Cell 2011 Apr 1;145(1):145-58
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All: |
1 reference(s)
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Analysis Tools
