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| Nomenclature |
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Symbol:
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Map2k7tm1.1Twad
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Name:
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mitogen-activated protein kinase kinase 7;
targeted mutation 1.1, Teiji Wada
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MGI ID: |
MGI:4948950 |
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Synonyms: |
Map2k7fl, Mkk7fl |
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Gene:
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Map2k7
Location:
Chr8:4238740-4251423 bp, + strand
Genetic Position: Chr8,
1.99 cM, cytoband A1.1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:170904
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Parent Cell Line:
| A9 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd x C57BL/6J
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 3. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 10. Flp-mediated recombination removed the neo cassette, leaving exons 3 through 10 floxed. (J:170904)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Map2k7 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:170904
Schramek D et al.,
"The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression."
Nat Genet 2011 Mar;43(3):212-9
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All: |
2 reference(s)
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Analysis Tools
