|
|
| Nomenclature |
|
Symbol:
|
Cd59a/Cd59btm1Jha
|
|
Name:
|
CD59b antigen;
targeted mutation 1, Jose A Halperin
|
|
MGI ID: |
MGI:4947112 |
|
Synonyms: |
mCd59ab- |
|
Gene:
|
Cd59b
Location:
Chr2:104069849-104091187 bp, + strand
Genetic Position: Chr2,
54.51 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:170754
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
129/Sv
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intergenic deletion |
| |
|
Mutation details: A neo cassette replaced exons 1 and 2 of Cd59a and exon 4 of Cd59b. The absence of either protein was confirmed by FACS analysis on platelets. (J:170754)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Cd59b Mutation:
|
4 strains or lines available |
|
| References |
|
Original: |
J:170754
Qin X et al.,
"Generation and phenotyping of mCd59a and mCd59b double-knockout mice."
Am J Hematol 2009 Feb;84(2):65-70
|
|
All: |
3 reference(s)
|
|
Analysis Tools
