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| Nomenclature |
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Symbol:
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Tg(NEFH)398Jpj
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Name:
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transgene insertion 398, Jean-Pierre Julien
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MGI ID: |
MGI:4947051 |
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Synonyms: |
NF-H44 |
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Transgene:
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Tg(NEFH)398Jpj
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The genomic fragments containing the human NEFH gene, flanked by 5'-promoter region and 3' sequences, coding for 44 Lys-Ser-Pro (KSP) phosphorylation sites, was used for the transgene. The total amount of protein detected in cytoskeletal-enriched preparations of the spinal cord corresponds to about two-fold the level detected in normal mice as determined by Coomassie blue after SDS/PAGE. (J:69179)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:69179
Couillard-Despres S et al.,
"Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase."
Proc Natl Acad Sci U S A 1998 Aug 4;95(16):9626-30
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All: |
1 reference(s)
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Analysis Tools
