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| Nomenclature |
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Symbol:
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Artm3.1(AR)Ska
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Name:
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androgen receptor;
targeted mutation 3.1, Shigeaki Kato
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MGI ID: |
MGI:4946660 |
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Synonyms: |
ARflox, ArL2 |
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Gene:
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Ar
Location:
ChrX:98149721-98323215 bp, + strand
Genetic Position: ChrX,
42.82 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:170092
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Parent Cell Line:
| TT2 (ES Cell) |
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Strain of Origin:
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(C57BL/6NCrlj x CBA/JNCrlj)F1
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 6 through 8 were replaced with a floxed cDNA of the corresponding human sequence, a neo cassette with a 3' loxP site, and a cDNA of the corresponding human sequence with nucleotide substitutions that result in the amino acid substitution of alanine for threonine at position 877. Cre-mediated recombination removed the neo cassette. (J:170092)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:170092
Takahashi S et al.,
"Noncanonical Wnt signaling mediates androgen-dependent tumor growth in a mouse model of prostate cancer."
Proc Natl Acad Sci U S A 2011 Mar 22;108(12):4938-43
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All: |
1 reference(s)
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Analysis Tools
