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| Nomenclature |
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Symbol:
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Tg(Ins2-Hnf1a)#Cbw
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Name:
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transgene insertion, Claes B Wollheim
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MGI ID: |
MGI:4942165 |
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Synonyms: |
RIP-DNHNF1alpha |
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Transgene:
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Tg(Ins2-Hnf1a)#Cbw
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x CBA/J)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The rat promoter drives beta cell expression of a cDNA for a dominant negative product that lacks 83 amino acids in the DNA-binding domain. (J:134757)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:134757
Hagenfeldt-Johansson KA et al.,
"Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice."
Endocrinology 2001 Dec;142(12):5311-20
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All: |
2 reference(s)
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Analysis Tools
