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| Nomenclature |
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Symbol:
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Slc6a8tm1.1Clar
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Name:
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solute carrier family 6 (neurotransmitter transporter, creatine), member 8;
targeted mutation 1.1, Joseph Clark
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MGI ID: |
MGI:4941753 |
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Synonyms: |
CrTflox |
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Gene:
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Slc6a8
Location:
ChrX:73673150-73682502 bp, + strand
Genetic Position: ChrX,
37.38 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:169472
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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C57BL/6
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette, leaving exons 2, 3, and 4 floxed. (J:169472)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:169472
Skelton MR et al.,
"Creatine transporter (CrT; Slc6a8) knockout mice as a model of human CrT deficiency."
PLoS One 2011;6(1):e16187
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All: |
2 reference(s)
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Analysis Tools
