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| Nomenclature |
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Symbol:
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Hand2tm2.1Dsr
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Name:
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heart and neural crest derivatives expressed transcript 2;
targeted mutation 2.1, Deepak Srivastava
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MGI ID: |
MGI:4940061 |
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Synonyms: |
Hand2loxp |
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Gene:
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Hand2
Location:
Chr8:57320983-57324517 bp, + strand
Genetic Position: Chr8,
29.8 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:169213
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette. (J:169213)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hand2 Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:169213
Tsuchihashi T et al.,
"Hand2 function in second heart field progenitors is essential for cardiogenesis."
Dev Biol 2011 Mar 1;351(1):62-69
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All: |
2 reference(s)
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