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| Nomenclature |
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Symbol:
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Gfi1Gen
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Name:
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growth factor independent 1;
Genista
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MGI ID: |
MGI:4881336 |
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Synonyms: |
Gen, Genista, Gfi1Genista |
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Gene:
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Gfi1
Location:
Chr5:107716657-107726036 bp, - strand
Genetic Position: Chr5,
52.23 cM
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Mutation origin |
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Strain of Origin:
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C57BL/6J
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Mutation description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: ENU induces a point mutation in zinc finger domain III that results in the amino acid substitution of tyrosine for cysteine at position 318 (C318Y). (J:182679)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:182679
Jaeger BN et al.,
"Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis."
J Exp Med 2012 Mar 12;209(3):565-80
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All: |
2 reference(s)
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