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| Nomenclature |
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Symbol:
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Mmp14tm1.1Khol
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Name:
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matrix metallopeptidase 14 (membrane-inserted);
targeted mutation 1.1, Kenn Holmbeck
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MGI ID: |
MGI:4868413 |
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Synonyms: |
MT1-MMPLoxP |
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Gene:
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Mmp14
Location:
Chr14:54431604-54441258 bp, + strand
Genetic Position: Chr14,
27.79 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:167396
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 2, and an additional loxP site was inserted downstream of eoxn 5. Flp-mediated recombination removed the neo cassette leaving exons 2 through 5 floxed. (J:167396)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mmp14 Mutation:
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9 strains or lines available |
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| References |
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Original: |
J:167396
Szabova L et al.,
"Membrane-type MMPs are indispensable for placental labyrinth formation and development."
Blood 2010 Dec 16;116(25):5752-61
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All: |
1 reference(s)
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Analysis Tools
