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| Nomenclature |
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Symbol:
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Mmp15tm1Kohl
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Name:
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matrix metallopeptidase 15;
targeted mutation 1, Kenn Holmbeck
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MGI ID: |
MGI:4868411 |
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Gene:
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Mmp15
Location:
Chr8:95352268-95374293 bp, + strand
Genetic Position: Chr8,
47.12 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:167396
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Parent Cell Line:
| W4 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Part of exon 2 through exon 5 was replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR on embryo extracts. (J:167396)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mmp15 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:167396
Szabova L et al.,
"Membrane-type MMPs are indispensable for placental labyrinth formation and development."
Blood 2010 Dec 16;116(25):5752-61
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All: |
1 reference(s)
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Analysis Tools
