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| Nomenclature |
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Symbol:
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Tg(H2-K/Igh-Traf2*)#Ywc
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Name:
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transgene insertion, Yongwon Choi
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MGI ID: |
MGI:4850018 |
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Synonyms: |
TRAF2.DN, Traf2DN-tg |
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Transgene:
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Tg(H2-K/Igh-Traf2*)#Ywc
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x CBA/J)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The H2-K promoter and an Igh enhancer from the pHSE-3' vector drives B and T cell-specific expression of a fragment of murine Traf2 (241-501), a dominant negative form, tagged with the 1D4-epitope. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:166886)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:166886
Lee SY et al.,
"TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival."
Immunity 1997 Nov;7(5):703-13
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All: |
4 reference(s)
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Analysis Tools
