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| Nomenclature |
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Symbol:
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Pik3cbtm1.1Rzl
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Name:
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phosphatidylinositol 3-kinase, catalytic, beta polypeptide;
targeted mutation 1.1, Richard Z Lin
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MGI ID: |
MGI:4845857 |
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Synonyms: |
p110betaflox, pik3cb3/4 loxP |
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Gene:
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Pik3cb
Location:
Chr9:99038402-99140621 bp, - strand
Genetic Position: Chr9,
51.41 cM, cytoband E4
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:166421
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 3, and an FRT and loxP flanked neo cassette was inserted downstream of exon 4. Flp mediated recombination removed the neo cassette leaving exons 3 and 4 floxed. (J:166421)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pik3cb Mutation:
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82 strains or lines available |
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| References |
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Original: |
J:166421
Lu Z et al.,
"Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction."
Circulation 2009 Jul 28;120(4):318-25
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All: |
5 reference(s)
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Analysis Tools
