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| Nomenclature |
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Symbol:
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Tg(Lck-Notch3)#Issc
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Name:
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transgene insertion, Isabella Screpanti
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MGI ID: |
MGI:4843437 |
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Synonyms: |
Notch3-IC, Notch3 tg(+), tg N3-IC |
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Transgene:
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Tg(Lck-Notch3)#Issc
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(DBA/2 x C57BL/6)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The mouse promoter drives thymocyte-specific expression of a truncated mouse cDNA encoding the intracellular domain with an HA tag and human growth hormone sequences and polyadenylation site. Fourteen founders were established. # is used when no specifc line is designated. (J:63300)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:63300
Bellavia D et al.,
"Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in notch3 transgenic mice"
EMBO J 2000 Jul 3;19(13):3337-48
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All: |
7 reference(s)
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Analysis Tools
