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| Nomenclature |
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Symbol:
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Tg(Thy1-APPSw)10Jiri
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Name:
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transgene insertion 10, Jill C Richardson
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MGI ID: |
MGI:4843212 |
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Synonyms: |
TAS10 |
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Transgene:
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Tg(Thy1-APPSw)10Jiri
Location:
unknown
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Transgene origin |
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Strain of Origin:
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C57BL/6 x C3H
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The promoter drives brain-specific expression of the human cDNA with the Swedish double familial mutation (K670N, M671L). Nine lines were generated and line 10 exhibits highest expression. (J:128647)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:128647
Richardson JC et al.,
"Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease."
Neuroscience 2003;122(1):213-28
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All: |
1 reference(s)
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