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| Nomenclature |
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Symbol:
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Tg(Sox3)1Pqt
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Name:
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transgene insertion 1, Paul Q Thomas
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MGI ID: |
MGI:4839388 |
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Synonyms: |
Sox3 transgene sex reversed, SR, Tg(Sox3-EGFP)SrPqt |
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Transgene:
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Tg(Sox3)1Pqt
Location:
unknown
Genetic Position: Chr19,
Syntenic
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Transgene origin |
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Strain of Origin:
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(C57BL/6 x CBA)F1
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: Two copies of the transgene, comprising approximately 36 kb of genomic sequence from the Sox3 locus followed by an internal ribosomal entry site (IRES) and a cDNA encoding enhanced green fluorescent protein (EGFP), have integrated into Chr 19 at bands B/C1, upstream of the aldehyde dehydrogenase superfamily 1, subfamily A1 gene. (J:171839)
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Inheritance: | |
Not Specified |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:171839
Sutton E et al.,
"Identification of SOX3 as an XX male sex reversal gene in mice and humans."
J Clin Invest 2011 Jan 4;121(1):328-41
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All: |
2 reference(s)
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