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| Nomenclature |
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Symbol:
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Nkaptm1.1Viss
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Name:
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NFKB activating protein;
targeted mutation 1.1, Virginia Shapiro
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MGI ID: |
MGI:4839023 |
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Synonyms: |
Nkapfl |
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Gene:
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Nkap
Location:
ChrX:37126795-37150746 bp, + strand
Genetic Position: ChrX,
21.54 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:165961
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 3 and an FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Flp mediated recombination removed the neo cassette leaving exons 3 and 4 floxed. (J:165961)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Nkap Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:165961
Pajerowski AG et al.,
"NKAP is a transcriptional repressor of notch signaling and is required for T cell development."
Immunity 2009 May;30(5):696-707
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All: |
3 reference(s)
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Analysis Tools
