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| Nomenclature |
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Symbol:
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Tg(tetO-Bmpr2*R899X)#Jwst
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Name:
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transgene insertion, James West
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MGI ID: |
MGI:4838675 |
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Synonyms: |
TetO7-BMPR2R899X |
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Transgene:
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Tg(tetO-Bmpr2*R899X)#Jwst
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A septad of tetracycline respons element with a minimal CMV promoter drive inducible expression of the mouse cDNA with nucleotide substitutions that result in the amino acid substitution of a stop codon for arginine at position 899 (R899X). The cDNA has a C-terminal FLAG tag and is followed by the beta-globin intron and polyadenylation sequence. The amino acid substitution does not alter SMAD activity. No line number or name was provided (designated by #). (J:142266)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:142266
West J et al.,
"Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions."
Am J Physiol Lung Cell Mol Physiol 2008 Nov;295(5):L744-55
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All: |
5 reference(s)
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Analysis Tools
