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| Nomenclature |
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Symbol:
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Chd7tm1.1Dmm
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Name:
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chromodomain helicase DNA binding protein 7;
targeted mutation 1.1, Donna M Martin
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MGI ID: |
MGI:4835266 |
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Synonyms: |
Chd7flox |
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Gene:
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Chd7
Location:
Chr4:8690406-8867659 bp, + strand
Genetic Position: Chr4,
3.68 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:164582
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Parent Cell Line:
| W4 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted up stream of exon 2 and an FRT flanked neo/kan cassette and second loxP site were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo/kan cassette. (J:164582)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Chd7 Mutation:
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38 strains or lines available |
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| References |
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Original: |
J:164582
Hurd EA et al.,
"The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear."
Development 2010 Sep;137(18):3139-50
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All: |
2 reference(s)
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Analysis Tools
