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| Nomenclature |
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Symbol:
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Cep290tm1Jgg
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Name:
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centrosomal protein 290;
targeted mutation 1, Joseph Gleeson
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MGI ID: |
MGI:4835225 |
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Synonyms: |
Cep290 floxed |
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Gene:
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Cep290
Location:
Chr10:100488289-100573655 bp, + strand
Genetic Position: Chr10,
51.48 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:172420
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Exons 36, 37 and the intervening intronic sequence were replaced by a targeting cassette containing "loxP-exon36-intron-exon37-loxP-neomycin resistance-loxP". Subsequent cre excision eliminated exons 36 and 37. (J:172420)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:172420
Lancaster MA et al.,
"Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome."
Nat Med 2011 Jun;17(6):726-31
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All: |
1 reference(s)
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Analysis Tools
