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| Nomenclature |
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Symbol:
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Tg(MMTV-PTGS2)#Thla
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Name:
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transgene insertion, Timothy Hla
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MGI ID: |
MGI:4834855 |
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Synonyms: |
MMTV-COX-2 |
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Transgene:
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Tg(MMTV-PTGS2)#Thla
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The mouse mammary tumor virus promoter drives expression of human PTGS2. Three founders were created, but no line numbers were provided. Low levels of transgene expression were detected in the mammary gland in mature virgin females and expression levels were significantly induced during pregnancy and lactation. (J:68565)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:68565
Liu CH et al.,
"Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice."
J Biol Chem 2001 May 25;276(21):18563-9
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All: |
3 reference(s)
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Analysis Tools
