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| Nomenclature |
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Symbol:
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Eomestm1.1Bflu
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Name:
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eomesodermin homolog (Xenopus laevis);
targeted mutation 1.1, Binfeng Lu
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MGI ID: |
MGI:4830338 |
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Gene:
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Eomes
Location:
Chr9:118478212-118486132 bp, + strand
Genetic Position: Chr9,
70.21 cM, cytoband F3
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:163822
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: The second exon was floxed and a FRT flanked neo cassette inserted within intron 2 by homologous recombination. The selection cassette was removed by Flp mediated recombination. (J:163822)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:163822
Zhu Y et al.,
"T-bet and Eomesodermin are required for T cell-mediated antitumor immune responses."
J Immunol 2010 Sep 15;185(6):3174-83
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All: |
2 reference(s)
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