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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm1(Foxo1)Jnk
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 1, Jun Nakae
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MGI ID: |
MGI:4820846 |
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Synonyms: |
R26floxneodelta256FoxO1 |
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Gene:
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Gt(ROSA)26Sor
Location:
Chr6:113067428-113077333 bp, - strand
Genetic Position: Chr6,
52.73 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:162892
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: An expression cassette containing a floxed neo-STOP cassette followed by a FLAG-tagged mouse cDNA truncated at amino acid 256 deleting the transactivation domain was inserted into the locus. Cre mediated expression is required to achieve expression of the truncated cDNA. (J:162892)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gt(ROSA)26Sor Mutation:
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191 strains or lines available |
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| References |
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Original: |
J:162892
Iskandar K et al.,
"PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake."
Am J Physiol Endocrinol Metab 2010 Apr;298(4):E787-98
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All: |
1 reference(s)
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Analysis Tools
