|
|
| Nomenclature |
|
Symbol:
|
Tg(Myh6-TNNT2*R141W)#Ajm
|
|
Name:
|
transgene insertion, Ali J Marian
|
|
MGI ID: |
MGI:4819721 |
|
Synonyms: |
cTnT-W141 |
|
Transgene:
|
Tg(Myh6-TNNT2*R141W)#Ajm
Location:
unknown
|
|
Transgene
origin |
|
Strain of Origin:
|
C3H and C57BL/6 and ICR
|
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: This transgene consists of a 5.5 Kb fragment of the mrine Myh6 promoter driving expression of a full length human TNNT2 cDNA containing a substitution that results in an Arg 141 Trp mutation. (J:161899)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:161899
Lombardi R et al.,
"Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies."
Cardiovasc Res 2008 Jul 1;79(1):109-17
|
|
All: |
1 reference(s)
|
|
Analysis Tools
