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| Nomenclature |
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Symbol:
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Tg(Tnnt2-TNNT2*R92Q)#Ajm
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Name:
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transgene insertion, Ali J Marian
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MGI ID: |
MGI:4819718 |
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Synonyms: |
cTnT-Q92 |
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Transgene:
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Tg(Tnnt2-TNNT2*R92Q)#Ajm
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C3H and C57BL/6 and ICR
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of a -497 bp fragment of the mouse Tnnt2 promoter driving expression of a full length human TNNT2 cDNA containing a G to A substitution that results in an Arg 92 Gln mutation. Five lines were generated (M-1, M-2, M-3, M-4. M-5) this record represents data for pooled or unspecified lines. (J:117554)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:117554
Oberst L et al.,
"Dominant-negative effect of a mutant cardiac troponin T on cardiac structure and function in transgenic mice."
J Clin Invest 1998 Oct 15;102(8):1498-505
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All: |
2 reference(s)
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Analysis Tools
