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| Nomenclature |
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Symbol:
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Tg(Thy1-BACE1)54/4Ppa
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Name:
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transgene insertion 54/4, Paolo Paganetti
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MGI ID: |
MGI:4819402 |
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Synonyms: |
BACE54 |
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Transgene:
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Tg(Thy1-BACE1)54/4Ppa
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6J
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A human BACE1 cDNA was placed under the control of the murine Thy-1 minigene. High levels of huBACE were observed in all analysed animals of the BACE54/4 line. (J:75039)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:75039
Bodendorf U et al.,
"Expression of human beta-secretase in the mouse brain increases the steady-state level of beta-amyloid."
J Neurochem 2002 Mar;80(5):799-806
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All: |
2 reference(s)
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Analysis Tools
