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| Nomenclature |
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Symbol:
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Tg(STIL-TAL1)A5(3)Alpa
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Name:
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transgene insertion A5(3), Peter Alpan
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MGI ID: |
MGI:4819165 |
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Synonyms: |
pSIL/TSCL |
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Transgene:
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Tg(STIL-TAL1)A5(3)Alpa
Location:
unknown
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Transgene origin |
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Strain of Origin:
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(C57BL/10Ros x C3H/HeRos)F1
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The transgene contains a fusion of the human promoter and exon 1 to the human cDNA spanning encoding amino acids 176 through 331 of TAL1. This original fusion was isolated from cell line CEM and subsequently truncated. Founders A5(1), A5(2), A5(3) and A5(4) were generated. (J:40868)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:40868
Aplan PD et al.,
"An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice."
EMBO J 1997 May 1;16(9):2408-19
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All: |
2 reference(s)
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