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| Nomenclature |
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Symbol:
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Zfp36l2tm1.1Tnr
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Name:
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zinc finger protein 36, C3H type-like 2;
targeted mutation 1.1, Martin Turner
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MGI ID: |
MGI:4819156 |
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Synonyms: |
Zfp36l2fl, Zfp36l2tm1.1Trn |
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Gene:
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Zfp36l2
Location:
Chr17:84183931-84187947 bp, - strand
Genetic Position: Chr17,
55.02 cM, cytoband E4
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:162388
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: LoxP sites were inserted to flank exon 2. The Neo cassette was removed from the germline by Flpe mediated recombination. (J:162388)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Zfp36l2 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:162388
Hodson DJ et al.,
"Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia."
Nat Immunol 2010 Aug;11(8):717-24
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All: |
1 reference(s)
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