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| Nomenclature |
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Symbol:
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Tg(tetO-NEFL)173.2Jpj
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Name:
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transgene insertion 173.2, Jean-Pierre Julien
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MGI ID: |
MGI:4819012 |
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Synonyms: |
Tg(hNF-LP22S) |
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Transgene:
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Tg(tetO-NEFL)173.2Jpj
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x C3H)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The tetracycline responsive element (TRE), minimal CMV promoter fused to the tetracycline operator, drives conditional expression of the human cDNA with nucleotide substitutions that result in the amino acid substitution of serine for proline at position 22 (P22S). Three lines were established (173.2, 173.3, and 176). (J:160704)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:160704
Dequen F et al.,
"Reversal of neuropathy phenotypes in conditional mouse model of Charcot-Marie-Tooth disease type 2E."
Hum Mol Genet 2010 Jul 1;19(13):2616-29
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All: |
1 reference(s)
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Analysis Tools
