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| Nomenclature |
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Symbol:
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Tg(Prnp-APP*)1Hmor
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Name:
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transgene insertion 1, Hiroshi Mori
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MGI ID: |
MGI:4818971 |
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Synonyms: |
APPE693delta |
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Transgene:
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Tg(Prnp-APP*)1Hmor
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6N x C3H/HeN)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The mouse promoter drives expression of the human cDNA with nucleotide deletions that result in the deletion of aspartic acid at position 693 (E693delta). Three lines were generated (lines 1, 2, and 3) with high, low, and intermediate expression levels, respectively. (J:123688)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:123688
Matsuyama S et al.,
"Inverse correlation between amyloid precursor protein and synaptic plasticity in transgenic mice."
Neuroreport 2007 Jul 2;18(10):1083-7
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All: |
3 reference(s)
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Analysis Tools
