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| Nomenclature |
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Symbol:
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Acdtm1.1Blas
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Name:
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adrenocortical dysplasia;
targeted mutation 1.1, Maria A Blasco
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MGI ID: |
MGI:4462417 |
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Synonyms: |
Tpp1flox |
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Gene:
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Acd
Location:
Chr8:105698159-105701095 bp, - strand
Genetic Position: Chr8,
53.04 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:160600
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: An FRT flanked neo cassette and a loxP site were inserted in exon 1 and a second loxP site was inserted in intron 4. The neomycin selection cassette was excised using Flp recombinase. (J:160600)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Acd Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:160600
Tejera AM et al.,
"TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice."
Dev Cell 2010 May 18;18(5):775-89
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All: |
1 reference(s)
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Analysis Tools
